Compare - Advantage Multi (Advocate) to Effipro DUO Spot-On

paranameorder_byAdvantage Multi (Advocate)Effipro DUO Spot-On
Kill Fleas501
Repels Fleas502
Kills Flea Eggs503
kills flea Larvae504
Kill Ticks505
Repels Ticks506
Effective against 4 ticks species507
Repels Mosquitoes508
Stop Fleas509Kills fleas within 12 hours Stops fleas within 24 hours
Effective Against Ticks510NO Controls ticks within 48 hours
Prevent Heartworm511
Other Parasites Information512Kills roundworms, hookworms, skinworms, whipworms and lungworms NA
Waterproof513
Dosage514Monthly Monthly
Application515Topical Topical
Taste516N/A NA
Effective When given with or without Food517N/A NA
Safe for pregnant or nursing Pets518
Active Ingredients519Imidacloprid, Moxidectin Fipronil, Pyriproxyfen
Usage520
Sizes Available521
  • For Small Dogs 3-9 lbs (Green)
  • For Medium Dogs 9.1-20 lbs (Aqua)
  • For Large Dogs 20.1-55 lbs (Red)
  • For Extra Large Dogs 55.1-88 lbs (Blue)
  • For Small Dogs up to 22 lbs.
  • For Medium Dogs 23 to 44 lbs.
  • For Large Dogs 45 to 88 lbs. 
  • For Extra Large Dogs Over 88 lbs.
Direction of Use522
  • Part the fur between the shoulder blades.
  • Squeeze out the entire content of the applicator at the spot.
  • For large dogs, apply at 2 to 3 spots starting from neck to tail.
  • Part the fur at the back on the shoulder blades until skin is visible.
  • Place the pipette and squeeze empty the entire content at the spot.
  • For larger dogs, apply at three to four spots.
Expert Tips523Do not apply if your pet is wet. Ensure your dog does not lick the treated area until dry.
What Veterinarian Says524Advocate is a convenient flea and heartworm preventive. It provides broad protection against numerous parasites. The topical solution provides wider coverage to control developmental stages of fleas. This one provides long lasting protection up to 3 months against flea life cycle. Usually helpful in controlling flea allergy dermatitis and diseases caused due to flea bites. It is highly recommended due to the proactive approach to flea management.
Age to Start525Puppies of 7 weeks of age Puppies 10 weeks of age
Caution526Do not apply on broken skin. Do not use in cases of known hypersensitivity to the active substances or to any of the excipients.
Human Safety527Do not drink or smoke while applying the product. Do not smoke, drink or eat during application. Wash hands after use.