Compare - Advantage Multi (Advocate) to Frontline Plus

paranameorder_byAdvantage Multi (Advocate)Frontline Plus
Kill Fleas501
Repels Fleas502
Kills Flea Eggs503
kills flea Larvae504
Kill Ticks505
Repels Ticks506
Effective against 4 ticks species507
Repels Mosquitoes508
Stop Fleas509Kills fleas within 12 hours Stops fleas within 12 hours
Effective Against Ticks510NO Ticks within 48 hours
Prevent Heartworm511
Other Parasites Information512Kills roundworms, hookworms, skinworms, whipworms and lungworms Treats chewing lice and controls sarcoptic mange infestations.
Waterproof513
Dosage514Monthly Monthly
Application515Topical Topical
Taste516N/A NA
Effective When given with or without Food517N/A NA
Safe for pregnant or nursing Pets518
Active Ingredients519Imidacloprid, Moxidectin Fipronil, (S)-Methoprene
Usage520
Sizes Available521
  • For Small Dogs 3-9 lbs (Green)
  • For Medium Dogs 9.1-20 lbs (Aqua)
  • For Large Dogs 20.1-55 lbs (Red)
  • For Extra Large Dogs 55.1-88 lbs (Blue)
  • for Small Dogs up to 22lbs (Orange)
  • for Medium Dogs 23-44 lbs (Blue)
  • for Large Dogs 45-88 lbs (Purple)
  • for Extra Large Dogs over 89 lbs (Red)
Direction of Use522
  • Part the fur between the shoulder blades.
  • Squeeze out the entire content of the applicator at the spot.
  • For large dogs, apply at 2 to 3 spots starting from neck to tail.
  • Part the fur between the shoulder blades to make the skin visible.
  • Open the pipette squeeze out the entire content on the skin without touching the hair.
  • For large and extra large dogs, apply at 3 to 4 spots on the back starting from neck to the base of the tail.
Expert Tips523Do not apply if your pet is wet. Do not allow your dog get immediately after treatment. At least wait for 24 hours for high efficacy.
What Veterinarian Says524Advocate is a convenient flea and heartworm preventive. It provides broad protection against numerous parasites. It's quite a popular product and vet's #1 choice due to its effectiveness. The potent combination of adulticide and insect growth regulator makes it work against not only adult fleas and ticks but also flea life cycle. In 99.9 cases, re-infestation is under control when Frontline Plus is used monthly without any breaks. It is usually recommended to use this product even in winters to protect against flea and tick infestation during the onset of summers.
Age to Start525Puppies of 7 weeks of age From 8 weeks of age and above.
Caution526Do not apply on broken skin. N/A
Human Safety527Do not drink or smoke while applying the product. N/A