Compare - Nexgard to Simparica TRIO

paranameorder_byNexgardSimparica TRIO
Kill Fleas501
Repels Fleas502
Kills Flea Eggs503
kills flea Larvae504
Kill Ticks505
Repels Ticks506
Effective against multiple tick species507
Repels Mosquitoes508
Stop Fleas509Kills 100% fleas within 24 hours Begins to kill fleas within 4 hours and demonstrated 100% effectiveness at 8 hours after administration.
Effective Against Ticks510Removes ticks within 48 hours Treats and controls black-legged tick, American dog tick, brown dog tick, lone star tick, Gulf-coast tick.
Prevent Heartworm511
Other Parasites Information512No No
Waterproof513
Dosage514Monthly Monthly
Application515Oral Oral
Taste516Beef-flavored chewable Flavored chewable
Effective When given with or without Food517Yes Can be given with or without food.
Safe for pregnant or nursing Pets518
Active Ingredients519AfoxolanerSarolaner, Moxidectin
Form/Type520
Sizes Available521
  • For Small Dogs 0 to 10lbs (Orange)
  • For Medium Dogs 10-24 lbs (Blue)
  • For Large Dogs 24-60 lbs (Purple)
  • For Extra Large Dogs 60 to 120lbs (Red)
  • For Dogs 2.8-5.5 lbs
  • For Dogs 5.6-11.0 lbs
  • For Dogs 11.1-22.0 lbs
  • For Dogs 22.1-44.0 lbs
  • For Dogs 44.1-88.0 lbs
  • For Dogs 88.1-132.0 lbs
Direction of Use522
  • Administer according to dog's weight.
  • Can be administered with or without food.
  • Treat all pets within the household.
  • Choose an appropriate pack based on your pet’s weight
  • Administer orally once a month with or following food
  • Treat on or about the same day each month
  • Begin at any time of the year and continue year-round without interruption
Expert Tips523For high effectiveness, ensure the pet takes complete dose.
  • Use Simparica Trio as part of a comprehensive parasite prevention plan
What Veterinarian Says524With many pet owners not feasible of using topical treatments to control fleas, Nexgard has turned out as the better option. The oral chew is easy for pet owners to administer and there have been no known side effects seen until now. This new product is loved by dogs because of their soft, beef flavored chewable.
  • Simparica Trio is a comprehensive and effective monthly chewable that protects dogs against fleas, ticks, heartworms, and intestinal worms, making it a convenient all-in-one solution for parasite prevention
Minimum Age525From 8 weeks of age 8 weeks of age (dogs and puppies)
Caution526For use in dogs only. Do not use in cats. Consult your vet before using in pets with history of seizures or neurologic disorders
Human Safety527Keep out of reach of children. Wash your hands thoroughly with soap and warm water after handing the product